About Us
The University of Toledo Department of Pathology Electron Microscopy Laboratory is
a state-of-the-art facility that specializes in ultrastructural diagnosis of human
disease and also provides research support as a university core laboratory. This
facility is located on the Health Science Campus of the University of Toledo. The
Electron Microscopy Facility is fully accredited, certified and licensed; copies of
our certification can be obtained via the following links: CLIA; CAP.
The laboratory is headed by William Gunning, PhD, who has extensive experience in both diagnostic and research applications of electron
microscopy. Dr. Gunning is a nationally recognized expert in the ultrastructural
evaluation of platelet dysfunction disorders with special emphasis on platelet dense
granule (delta) storage pool deficiency, a condition that can cause easy bruising
and frequent nose bleeds, and that appears to be common in women with clinically diagnosed
menorrhagia. Dr. Gunning also has extensive experience in the ultrastructural evaluation
of kidney, muscle, nerve, and neoplastic diseases. Additional diagnostic expertise
is provided by Robert Mrak, MD, PhD. Dr. Mrak has over 40 years of experience in the ultrastructural evaluation and
diagnosis of muscle, nerve, and brain biopsies, and of difficult and poorly differentiated
neoplasms. In addition to our diagnostic work, the laboratory supports research efforts
by scientists working in the fields of cancer biology, cardiovascular disease, diabetes,
immunology, and neuroscience research.